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Southern Style Cheesy Chicken Spaghetti Casserole Recipe

Southern Style Cheesy Chicken Spaghetti Casserole Recipe


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4.6 from 16 reviews

  • Total Time: 45-50 minutes
  • Yield: 6 1x

Description

Spicy Southern Cheesy Chicken Spaghetti Casserole brings Southern comfort right to your dinner table with a kick of heat and creamy goodness. Packed with tender chicken, melted cheese, and a zesty sauce, this casserole guarantees smiles around your family’s plate.


Ingredients

Scale

Main Protein:

  • 1 lb chicken shredded meat
  • 1 lb Velveeta cheese
  • 1 lb spaghetti (cooked)

Supporting Ingredients:

  • 1 cup milk
  • 1 10 oz can original Rotel
  • 1 10 oz can cream of mushroom soup
  • 1 cup shredded cheddar cheese

Finishing Ingredients:

  • 2 tablespoons unsalted butter
  • ½ cup panko bread crumbs
  • salt and pepper (to taste)
  • crushed red pepper flakes (for serving)

Instructions

  1. Grease a 9×13 inch casserole dish with Crisco, ensuring every corner is covered. Set the oven to precisely 350 degrees F.
  2. In a large stockpot, melt 2 tablespoons unsalted butter over medium heat. Add 1 pound Velveeta cheese chunks, 1 can Rotel, 1 can cream of mushroom soup, and 1 cup milk.
  3. Stir the mixture continuously until the Velveeta completely melts and creates a smooth, creamy sauce, about 5-6 minutes.
  4. Add 1 pound shredded rotisserie chicken and 1 pound cooked spaghetti to the pot. Season with salt and pepper to your taste.
  5. Gently fold all ingredients together, ensuring the pasta and chicken are evenly coated with the cheese sauce.
  6. Transfer the entire mixture into the prepared casserole dish, spreading it evenly with a spoon.
  7. Sprinkle 1 cup shredded cheddar cheese across the top of the casserole, then dust with ½ cup panko bread crumbs for a crispy texture.
  8. Cover the dish tightly with aluminum foil and bake at 350 degrees F for exactly 30 minutes.
  9. Remove the foil and broil for 3-4 minutes, watching carefully to prevent burning until bread crumbs turn golden brown.
  10. Let the casserole rest for 5 minutes after removing from the oven to allow the sauce to set.
  11. Serve hot, sprinkling crushed red pepper flakes on top according to your spice preference.

Notes

  • Swap out regular spaghetti for whole wheat or gluten-free pasta to make this dish more diet-friendly.
  • For a lighter version, use reduced-fat cheese and low-sodium cream of mushroom soup.
  • Rotisserie chicken works perfectly as a time-saving protein alternative to cooking chicken from scratch.
  • Always watch the broiling stage carefully, as breadcrumbs can burn quickly and ruin the entire casserole’s beautiful topping.
  • Prep Time: 10 minutes
  • Cook Time: 35-40 minutes
  • Category: Casseroles
  • Method: Baking
  • Cuisine: Southern American

Nutrition

  • Serving Size: 6
  • Calories: 577 kcal
  • Sugar: 3 g
  • Sodium: 690 mg
  • Fat: 34 g
  • Saturated Fat: 19 g
  • Unsaturated Fat: 13 g
  • Trans Fat: 0.5 g
  • Carbohydrates: 30 g
  • Fiber: 2 g
  • Protein: 32 g
  • Cholesterol: 110 mg