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Melty Pepperoni Pizza Casserole Recipe

Melty Pepperoni Pizza Casserole Recipe


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4.8 from 28 reviews

  • Total Time: 35-40 minutes
  • Yield: 6 1x

Description

Pepperoni Pizza Casserole brings all the cheesy, saucy goodness of pizza into a comforting baked dish that’ll make your family cheer at dinnertime. Packed with zesty pepperoni, melted cheese, and a hearty pasta base, this crowd-pleasing meal comes together faster than ordering delivery.


Ingredients

Scale

Main Ingredients:

  • 1 package (16 ounces) rotini pasta
  • 1 jar (14 ounces) pizza sauce
  • 1 package (5 ounces) pepperoni slices

Supporting Ingredients:

  • 2 cups shredded mozzarella cheese
  • ½ cup grated Parmesan cheese

Seasonings:

  • 1 teaspoon dried oregano

Instructions

  1. Crank your oven to 375°F for a perfectly heated cooking environment.
  2. Salt a large pot of water and boil the entire 16-ounce package of rotini pasta until it reaches al dente texture, then drain completely.
  3. Grab a spacious mixing bowl and combine your cooked pasta with the full 14-ounce jar of pizza sauce, stirring in 1 cup of mozzarella cheese until everything is evenly coated.
  4. Transfer the saucy pasta mixture into a clean 9×13-inch baking dish, spreading it smoothly across the entire surface.
  5. Scatter the remaining 1 cup of mozzarella cheese generously over the pasta base, creating a complete cheese layer.
  6. Arrange the entire 5-ounce package of pepperoni slices across the cheese, covering most of the surface.
  7. Sprinkle the ½ cup of Parmesan cheese and 1 teaspoon of dried oregano over the top for an extra flavor boost.
  8. Slide the baking dish into the preheated 375°F oven and bake for exactly 22 minutes, watching for golden, bubbling cheese.
  9. Remove from the oven and let the casserole rest for 5 minutes before serving to allow the ingredients to settle.

Notes

  • Swap pepperoni for turkey pepperoni or veggie pepperoni to make the dish lighter and more diet-friendly.
  • Fresh mozzarella creates a creamier texture, while pre-shredded cheese melts more uniformly in the casserole.
  • Add extra vegetables like bell peppers or mushrooms to boost nutritional value and create more depth of flavor.
  • Let the casserole rest for 5-10 minutes after baking to help it set and make serving easier, preventing the cheese from running everywhere.
  • Prep Time: 15 minutes
  • Cook Time: 20-25 minutes
  • Category: Casseroles
  • Method: Baking
  • Cuisine: Italian-American

Nutrition

  • Serving Size: 6
  • Calories: 530 kcal
  • Sugar: 6 g
  • Sodium: 980 mg
  • Fat: 22 g
  • Saturated Fat: 10 g
  • Unsaturated Fat: 11 g
  • Trans Fat: 0.5 g
  • Carbohydrates: 50 g
  • Fiber: 3 g
  • Protein: 28 g
  • Cholesterol: 55 mg